Dr. Issels' therapeutic concept was not the aimless polypharmacy that many biased critics sometimes
claimed it was, but rather a well-thought-out combination of both specific and nonspecific remedies
and methods which had until then never been used against cancer in this form and systematology. The
patients' reactions were carefully noted and entered into the properly-kept temperature charts and medical
records. The patient remained in contact with the clinic even after termination or interruption of inpatient
treatment, by continuing from time to time to fill in and submit, as instructed, temperature charts
and therapy records, and then receiving in return new information, either for self-treatment or treatment
from the family doctor.
Dr. Issels' 1953 paper was followed in 1959 by an objective report from the Dutch oncologist Prof.
Audier on the course of illness of 252 patients with clinically-proven and documented malignomas who
had come to the clinic after having been declared "incurable". Under Dr. Issels' combination
therapy, 42 of these (i.e. 16.6%) survived symptom-free for the 5-year-term defined by orthodox medicine
as constituting "total remission".
Of Dr. Issels' numerous publications -- the author of this obituary has a compilation of these -- his
two main works should be emphasized: "More Cancer Cures" (1972) and "My Struggle against
Cancer" (1981).
Of course, criticism from colleagues was not lacking, considering the heretofore unprecedented healing
success being attained by these new methods. This culminated in the "Trial of the Century",
fabricated out of malice, denunciation and false accusations, engineered by the Bavarian Medical Council
under the leadership of its then-president Severing, which made its way through the court system for
4 years and led to the temporary closing of the clinic. In 1964, Dr. Issels was acquitted of all charges
and fully exonerated. In this, an expert opinion from Prof. Zabel, then also well known for his holistic
orientation, played a decisive role. It was a victory for progress over narrow-minded intolerant dogmatism.
Anyone fortunate enough to experience, as a co-worker, Dr. Issels' exemplary discipline, medical insight,
scientific meticulousness, therapeutic consistency, psychological skills and infectious optimism, even
in critical situations, will never forget these humanly and professionally formative impressions.